Research

The Cardiology Division is involved in a number of areas of clinical research, including multiple active national and international clinical trials. Major interests include reperfusion through thrombolysis, mechanisms of clot formation and dissolution, the role of platelets in unstable angina, restenosis following angioplasty and lipid disorders as they affect clot formation, restenosis, and atherogenesis. We are active in the investigation of interventional devices and strategies, and have been active participants in all of the major arrhythmia investigations. Our research is supported by three full time Research Nurses.

Basic investigation is conducted at the Maine Medical Center Research Institute (MMCRI). We are actively involved with the MMCRI Molecular Biology group in planning pre-clinical and clinical studies of FGF-4, and angiogenic protein developed by the head of that group.

Fellows are expected to participate in ongoing research projects and to develop an investigative proposal that addresses a research question to be researched during their training. Developed under the guidance of a faculty preceptor, proposals are critiqued by cardiology faculty and senior investigators from MMCRI. Fellows may apply for research grants through the MMCRI Mentored Research Grants Program. Laboratory support for bench research studies is provided by the MMCRI. In addition, fellows have access to experienced basic and clinical research mentors, on-site statisticians, and analysts to assist in developing, performing, and analyzing the data from their research projects. A listing of current publications is available on request.

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