Scholarly Activity

Ongoing Prospective Projects

• Quaye, Jenson--Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Use in Patients with Chronic Non-Cancer Pain (a collaboration with MGH). Recruitment and data collection is in progress.
• Mountjoy, Quaye, Beeler, Nohr, O’Brien, Garcia, Finke, Jenson, Seely—A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Continuous Nerve Catheters on Pain Control and Post-Operative Opioid Use in Patients Receiving Popliteal Nerve Blocks for Below the Knee Amputation. Recruitment and data collection is in progress (10/30 patients).
• Quaye, Akobo—Survey study regarding patient attitudes and stigmas regarding MOUD treatment. IRB reviewed, data collection started in spring 2024.
• Smith, Adams, Spiro, Hicks, Hathaway—CRYPTICS Clinical trial (Design of the Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery - ScienceDirect)
• Quaye, Provider Survey, IRB reviewed, MaineHealth wide survey of critical care providers regarding management of patients with OUD and buprenorphine. Data collection began April 2024.
• Quaye, Critical Care Dashboard, IRB reviewed, creating a dashboard for critical care patients with OUD to improve care and access to resources. Going live fall 2024.
• Quaye, Wolf, Montague, Karunasiri, Kohutnicki-- An Initiative to Reduce Plastic Waste in ECT, IRB reviewed, trialing reusable circuits in ECT to improve efficiency and reduce waste. Data collection will be complete 8/26/2024.
• Kohunticki, Olson, Gagnon—MMC Anesthesia Gas Reduction. This first phase is happening now and includes interventions like supply chain/formulary changes (removed desflurane), infrastructural changes (piped N2O is getting replaced w E-cylinders), and changes in clinical practice (grand round talks, town hall reminders, EPIC dashboard that records calculated total usage and associated carbon footprint per provider, best practice advisories in EPIC will soon be implemented, etc).  There are a multitude of metrics we are monitoring with these changes, such as cost, savings, environmental impact, cultural shifts within the institution, etc.
• Hicks, Predicting, Preventing, and Reacting to Adverse Events in the Cardiothoracic Operating Room. IRB reviewed, exempt. Registry project with Roux Institute.
• Quaye, Peck—A prospective randomized trial of the effect of buprenorphine continuation on pain control and post-operative opioid use. Recruitment is closed due to low enrollment (12/80 patients). Results need to be posted to clinicaltrials.gov by September 2024.
• Longfellow, Murray, Abruzzese, Quaye - IRB approved (QI not research)- "New Algorithm for peripheral IV cannulation for patients with h/o difficult access"

Retrospective Work in Progress

• Hicks, A clinical comparison of rigid plate fixation and wire cerclage sternotomy closure: Proposal for a retrospective, propensity scored analysis. IRB approved retrospective record review, data collection in progress.
• Quaye, Beers-Mulroy study with OHDSI IRB approved “Predicting Persistent Opioid Use After Total Joint Arthroplasty” in progress, presented at 2023 ASA, manuscript revisions due September 2024
• Hubbs, Pepper, Fitzgerald—The implication of frailty for the surgical patient, a retrospective study. Additional data recently acquired, analysis in progress.
• Quaye, Flowerdew, Beers-Mulroy, Barker—The impact of timing and mode of TrueLearn Use on ITE scores. IRB approved writing in progress.
• Hackett, Osuchukwu, Brown- A single Institution Experience with a unliteral Liposomal Bupivacaine Transversus Abdominis Plane Block on postoperative pain and opioid prescription at discharge among patients undergoing Laparoscopic Donor Nephrectomy. Retrospective project, data analysis done.
• Quaye, Carroll—Changes in MOUD prescribing practices over time, retrospective study in progress, submitted to PGA

Publications

• Quaye A, Crist C, Matoi S, Zhang Y. Commentary on the current state of perioperative and critical care buprenorphine management. Addiction. 2024 Jan;119(1):200-201. doi: 10.1111/add.16346. Epub 2023 Sep 28. PMID: 37767982.
• Kellegrew J, Hicks A, Gill L, Chemmanam I, Mountjoy R. Diagnostic and Therapeutic Ilioinguinal and Iliohypogastric Nerve Blocks: A Case Report. A A Pract. 2024 Jan 23;18(1):e01740. doi: 10.1213/XAA.0000000000001740. PMID: 38259135.
• Quaye A, McAllister B, Garcia JR, Nohr O, Laduzenski SJ, Mack L, Kerr CR, Kerr DA, Razafindralay CN, Richard JM, Craig WY, Rodrigue S. A prospective, randomized trial of liposomal bupivacaine compared to conventional bupivacaine on pain control and postoperative opioid use in adults receiving adductor canal blocks for total knee arthroplasty. Arthroplasty. 2024 Feb 1;6(1):6. doi: 10.1186/s42836-023-00226-y. PMID: 38297390; PMCID: PMC10832097.
• Osuchukwu O, Gagnon J, Richard J, Craig W, Quaye A. Liposomal bupivacaine in transversus abdominis plane blocks for lower abdominal surgery. Pain Pract. 2024 Jun;24(5):717-723. doi: 10.1111/papr.13347. Epub 2024 Jan 24. PMID: 38265273; PMCID: PMC11178472.
• Quaye A, Mardmomen N, Mogren G, Ibrahim Y, Richard J, Zhang Y. Current State of Perioperative Buprenorphine Management-A National Provider Survey. J Addict Med. 2023 Nov-Dec 01;17(6):640-645. doi: 10.1097/ADM.0000000000001191. Epub 2023 Jun 5. PMID: 37934521.
• Quaye A, Wampole C, Riker RR, Seder DB, Sauer WJ, Richard J, Craig W, Gagnon DJ. Medications for opioid use disorder prescribed at hospital discharge associated with decreased opioid agonist dispensing in patients with opioid use disorder requiring critical care: A retrospective study. J Subst Use Addict Treat. 2023 Dec;155:209176. doi: 10.1016/j.josat.2023.209176. Epub 2023 Sep 29. PMID: 37778703; PMCID: PMC10715808.
• Quaye AN, Hisey WM, Mackenzie TA, Robinson CM, Richard JM, Anderson JC, Warters RD, Butterly LF. Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study. Anesthesiology. 2024 Jun 1;140(6):1088-1097. doi: 10.1097/ALN.0000000000004955. PMID: 38629957; PMCID: PMC11096037.
• Quaye A, Wampole C, Riker RR, Seder DB, Sauer WJ, Richard JM, Craig WY, Gagnon DJ. Buprenorphine Continuation During Critical Illness Associated With Decreased Inpatient Opioid Use in Individuals Maintained on Buprenorphine for Opioid Use Disorder in a Retrospective Study. J Clin Pharmacol. 2023 Sep;63(9):1067-1073. doi: 10.1002/jcph.2286. Epub 2023 Jun 7. PMID: 37204408; PMCID: PMC10524870.
• Gagnon DJ, Glenn MJ, Quaye AA, Erstad BL. Buprenorphine in the Intensive Care Unit: Commentary on the Unanswered Questions. Ann Pharmacother. 2024 May 16:10600280241254528. doi: 10.1177/10600280241254528. Epub ahead of print. PMID: 38755998.
• Quaye A, Tsafnat T, Richard JM, Stoddard H, Gagnon DJ. Post-operative pain control in patients on buprenorphine or methadone for opioid use disorder. J Opioid Manag. 2024 May-Jun;20(3):233-241. doi: 10.5055/jom.0823. PMID: 39017615.
• Stoker A, Hicks A, Wright MC, Ali A, Klapper J, Poisson J, Zaffiri L, Chen D, Hartwig M, Ghadimi K, Welsby I, Bottiger B. Development of New Donor-Specific and Human Leukocyte Antigen Antibodies After Transfusion in Adult Lung Transplantation. J Cardiothorac Vasc Anesth. 2023 Sep;37(9):1609-1617. doi: 10.1053/j.jvca.2023.04.038. Epub 2023 Apr 29. PMID: 37263806.
• Quaye A, Zhang Y. Letter to the editor: in response to “perioperative management of patients on buprenorphine for opioid use disorder.” ASRA Pain Medicine News 2023;48. https://doi.org/10.52211/asra080123.005

Invited Lectures

• Quaye A, "Buprenorphine use in the ICU", Critical Care department, 7/30/24 Conference Presentations

Presentations/Participation in Professional Activities

• Supp B, “Bi-Pella Support for Cardiac Protection in High-Risk Percutaneous Coronary Intervention”, poster, SCA Conference, Toronto Canada, April 2024
• LeSage B, “New Left Ventricular Outflow Tract Gradient Status Post Mitral Valve Replacement Not Just A Bioprosthetic Valve Concern”, poster, SCA Conference, Toronto Canada, April 2024
• Beers-Mulroy B, McAuley P, “Percutaneous Paravalvular Leak Closure Following Complicated Mitral Valve Replacement” poster, SCA Conference, Toronto Canada, April 2024
• Smith D, “Critical Procedure Workshop” SCA Conference, Toronto Canada, April 2024
• LeSage B, Weimer J, DeNino W, Link C, “Massive Pulmonary Embolism with Venoarterial Extracorporeal Membrane Oxygenation Rescue In A Patient Recently Started On Semaglutide: A Case Report” ASAIO Conference, First place, Baltimore, MD May 2024
• Carroll M, “Retained Epidural Catheter and Methods to Assist in Removal" Case Presentation ASRA, San Diego, March 2024
• Kerr C, Kerr D, Quaye A, "A randomized trial of liposomal bupivacaine compared to conventional bupivacaine in adults receiving adductor canal blocks for total knee arthroplasty" Case Presentation, ASRA, San Diego, March 2024
• Kinney J, Orff S, Begin R, Flavin N, Hyrkas E, Adams C, Neilson, “Risky Business: Creating a Process to Review Accuracy of American Society of Anesthesia (ASA) Classification and to Improve Overall Quality Risk Adjustment of Surgical Patients” Poster. Lambrew Research Retreat, Portland ME, May 2024
• Peck, M, Beers-Mulroy B, Richard J, Krulee R, Stoddard H, Kostka, DiPalazzo J, Quaye, A, “Characteristics Associated with Persistent Opioid Use Following Total Joint Arthroplasty” Poster. Lambrew Research Retreat, Portland ME, May 2024
• Kerr D, “A Prospective Randomized Trial of Liposomal Bupivacaine Compared to Conventional Bupivacaine on Pain Control and Post Operative Opioid Use in Adults Receiving Adductor Canal Blocks for Total Knee Arthroplasty ”, Poster awarded 1st place, Lambrew Research Retreat, Portland ME, May 2024
• Pepper K. Levin B, “Evaluation and Diagnosis of Peri-Operative Stroke in the Setting of Neuromuscular Blockade: A Case Study”, Case Report, ASA, San Francisco CA, October 2023
• Boyd C, Kellegrew J, Egan D. “Anesthetic Management of GLP-1 Agonists” MeSA PBLD, Carrabassett Valley Maine, Feb 2024
• Kwock J, Longfellow J, Watczak J, “Enhanced Recovery after Cesarean Section” MeSA PBLD, Carrabassett Valley Maine, Feb 2024
• Mountjoy R, Peck M, Olson B, “High Yield POCUS for Anesthesia” MeSA PBLD, Carrabassett Valley Maine, Feb 2024
• Abruzzese C, Gasperlin G, McAuley P, “Optimizing Ventilator Strategies in Morbidly Obese Patients” MeSA PBLD, Carrabassett Valley Maine, Feb 2024
• Pisini J, Pepper K, Woodward Z, “Peri-op Management of Torrential Tricuspid Regurgitation” MeSA PBLD, Carrabassett Valley Maine, Feb 2024
• Mountjoy R. “Nerve Block Ultrasound Clinic” MeSA Workshop, Carrabassett Valley Maine, Feb 2024
• Quaye A "Cannabinoids and Anesthesia" JAERJ conference Rio De Janiero, Brazil May 25, 2024
• Quaye A "Buprenorphine and Methadone" JAERJ conference Rio De Janiero, Brazil May 25, 2024
• Quaye A "Climate change and anesthesia" JAERJ conference Rio De Janiero, Brazil May 24, 2024
• Quaye A "Buprenorphine in the Perioperative Setting: Effective Management Strategies" University of Arkansas for Medical Sciences: January, 16 2024
• Quaye A "Perioperative Buprenorphine- Optimizing management strategies" University of Texas Health Center December, 8, 2023
• Quaye A “Perioperative Buprenorphine Management,” New Mexico Medical Society conference October 7, 2023
• Quaye A "Perioperative Buprenorphine- Optimizing management strategies" Tufts Medical Center, Boston, MA Grand Rounds:  October 19, 2023
• Quaye A "To Stop or not to stop; Buprenorphine and Acute pain management"  Lahey Hospital Grand Rounds:  April 12, 2023
• Quaye A "Perioperative Buprenorphine - Optimizing management strategies" Beth Israel Deaconess Medical Center Grand Rounds:  March 15, 2023
• Senior Grand Rounds – Gasper Gasperlin DO, “Artificial Intelligence in Anesthesiology”, Portland ME April 2024
• Senior Grand Rounds – Danielle Kerr DO, “Anesthetic Considerations in Athletes”, Portland ME May 2024
• Senior Grand Rounds – Christine Kerr DO, “Opium Addiction and Art”, Portland ME, May 2024
• Senior Grand Rounds – Meredith Peck DO, “Consciousness”, Portland ME May 2024
• Senior Grand Rounds Jay Kellegrew MD, “Learning and Teaching in the OR”, Portland ME May 2024
• Cardiac Conference Presentation, Jacob Longfellow DO, Portland, ME January 2024
• Cardiac Conference Presentation, Maggie Carroll MD, Portland, ME March 2024
• Cardiac Conference Presentation, Keating Pepper DO, Portland, ME April 2024
• Cardiac Conference Presentation, Michael Finke DO, Portland, ME April 2024
• Cardiac Conference Presentation, Charm Karunasiri MD, Portland, ME May 2024
• Cardiac Conference Presentation, Blaire Beers-Mulroy, Portland, ME February 2024

Leadership Positions

• Michael Henry, MD - Medical student clerkship director
• Jonathan Meserve, MD - Maine Medical Association Board of Directors, healthcare reform and bylaws subcommittee
• Jessica Hathaway, MD - MHMMC Executive Committee
• Adam O’Brien, DO – Secretary/Treasurer, MeSA

Faculty & Resident: Conferences Attended 2023-2024

• ASA Annual Meeting
• American Society Regional Anesthesia & Pain Medicine (ASRA)
• ASA Legislative Meeting
• ASA Annual Meeting
• ABA Board Examiners (Hathaway, Allyn)
• MITE Faculty Development Conference
• Maine Society of Anesthesiologists (MeSA)
• Society Pediatric Anesthesia
• Society Cardiovascular Anesthesiologists (SCA)
• International Anesthesia Research Society (IARS)
• International Meeting on Simulation in Healthcare
• Society of Academic Anesthesiology Association (SAAA)
• Association of Anesthesia Clinical Directors (AACD)
• Society for Education in Anesthesia (SEA)
• Principles of Medical Education, Maximizing Your Teaching Skills

Quaye, Budi, Peck, Silvia. A Prospective, Randomized Trial of the Effect of Buprenorphine Continuation on Pain Control and Post-Operative Opioid Use

Mountjoy, Quaye, Osuchukwu, Blazick, Branch. A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Continuous Nerve Catheters on Pain Control and Post-Operative Opioid Use in Receiving Popliteal Nerve Blocks for Below the Knee Amputation

Nohr, Quaye, Budi, Sutherland, Hunt. A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Conventional Bupivacaine on Pain Control and Postoperative Opioid Consumption in Patients Following Cesarean Delivery

McCallister, Laduzenski, Quaye, Kerr, Rodrigue. A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Conventional Bupivacaine on Pain Control and Post-Operative Opioid Use in Adults Receiving Adductor Canal Blocks for Total Knee Arthroplasty. Data collection is complete, writing is underway. To be submitted to Regional Anesthesia and Pain Medicine.

Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients with Chronic Non-Cancer Pain

Current Retrospective Projects

Budi, Quaye Post-Operative Pain Following Cesarean Section in Patients on Opioid Agonist Pharmacotherapy receiving postoperative ketamine infusions

Quaye Postoperative Pain Control in Patients on Buprenorphine, Methadone or Naltrexone Treatment for Opioid Use Disorder. Data collection and analysis complete. To be submitted to the Journal of Opioid Management.

Quaye, Zhang Perioperative Buprenorphine Management- A National Provider’s Survey. Complete and published in the Journal of Addiction Medicine.

Osuchukwu, Quaye Institutional Experience with Liposomal Versus Conventional Bupivacaine for Transversus Abdominis Plane Blocks in Abdominal Surgeries. In press with Pain Practice.

Quaye, Gagnon, Riker, Seder, Sauer Characteristics of patients maintained on Buprenorphine requiring Intensive Care Admission

• Two part study: descriptive analysis and retrospective 2:1 matched control comparative analysis. Published in the Journal of Clinical Pharmacology and in revisions with the Journal of Substance Use and Addiction Treatment.

Quaye, Kostka, Pallazzo Predicting Persistent opioid use in patients scheduled for elective total joint arthroplasty.

Budi, Quaye, Mountjoy Evaluation of Current STOP-BANG Screening Tool Policies

Hubbs, Hackett Quality Improvement Initiative to Improve the Detection and Treatment of Hyperglycemia in Diabetics and non-diabetics undergoing Neurosurgery, Vascular Surgery or ERAS protocols at Maine Medical Center

Hicks, Quaye, Barker, Hayes, Kramer Does preoperative hemoglobin level inversely correlate with risk of blood product transfusion in cardiac surgical patients at Maine Medical Center?

Submitted Papers (awaiting decision/recent decision notification)

Osuchukwu O, Gagnon J, Nohr, O, Richard, J, Craig, W, Quaye, A. Liposomal bupivacaine in transversus abdominis plane blocks for lower abdominal surgery. Pain practice (accepted pending revisions)

Quaye A, Wampole C, Riker R, Seder D, Sauer W, Richard J, Craig W, Gagnon D. Buprenorphine Prescribing at Hospital Discharge Associated with Decreased Opioid Agonist Dispensing in Patients with Opioid Use Disorder Requiring Critical Care: a retrospective study. Journal of Substance Abuse Treatment (accepted pending revisions)

Quaye A, Robinson C, Mackenzie T, Warters D, Butterly L. Propofol associated with increased serrated polyp detection during screening and surveillance colonoscopy. Submitted to anesthesiology 6/1/23

Kellegrew J, Hicks A, Gill L, Chemmanam I, Mountjoy R. Targeted Diagnostic and Therapeutic Ilioinguinal and Iliohypogastric Nerve Blocks: A Case Report. Submitted to A&A Practice.

Quaye, Zhang. Letter to the Editor: In Response to “Perioperative Management of Patients on Buprenorphine for Opioid Use Disorder” accepted to ASRA RAPM 6/23

Papers in Progress

Quaye, Stoddard, Richard, Gagnon, Zhang. Postoperative Pain Severity and Opioid Consumption in Patients on Buprenorphine or Methadone for the Treatment of Opioid Use Disorder. Manuscript in progress. To submit to journal of opioid management

Quaye, McAllister, Laduzenski, Mack, Kerr, Kerr, Nohr, Craig, Nrazafindralay, Rodrigue. Liposomal bupivacaine associated with decreased opioid utilization following total knee arthroplasty in randomized prospective trial. Manuscript in progress. Submitted to Regional anesthesia and pain medicine

Jenson, Branch, Quaye. Distinguishing between Phantom limb pain, limb sensations and residual limb pain, a literature review. Manuscript in progress

Projects in Development

TrueLearn project: Barker, Mulroy, Flowerdew, Quaye (data entry phase, IRB submitted)

Sustainability project: reducing anesthesia waste during ECT (proof of concept phase)

COBRE specific aims for improving opioid management/access and rural health

Dartmouth colonoscopy study collaboration. (one paper submitted; 3 more papers will come out of this collaboration - propofol and ADR/SDR; histology and location differences with propofol and polyp detection; propofol use over time

Invited Lectures

Swartz, B ECMO Conference-Critical Care department, 3/16/23 Conference Presentations

Presentations/Participation in Professional Activities

Quaye Invited speaker to Beth Israel Deaconess Medical Center Grand Rounds: Perioperative Buprenorphine - Optimizing management strategies 3/23

Quaye Invited speaker to Lahey Hospital Grand Rounds: To Stop or not to stop; Buprenorphine and Acute pain management 4/23

Quaye A. Optimizing Perioperative Buprenorphine Management in Patients with Opioid Use Disorder. Northern New England Center for Clinical and Translational Research Seminar Series. May 26, 2023

Jenson A, Jashinski J, Cloutier A, Eastman S, Pachas G, Evins E, Quaye A, Gilman J. Can Patients Taper Opioid Medication and Maintain Pain Control? A randomized trial of cannabis added to behavioral pain management among adults with chronic non-cancer pain. A collaboration with Massachusetts General Hospital. Presented at Costas T. Lambrew Research Retreat, May 2, 2023

McGrory B, Mountjoy R, Hubbs R, Rana A, Mackenzie J, Hersch M, Becker M, Colacchio N. The Use of the iPack Block with the Adductor Canal Block Decreases 48-hour Narcotic Usage and Postoperative Pain following Total Knee Arthroplasty. Presented at Costas T. Lambrew Research Retreat, May 2, 2023

Budi T, Richard J, Craig W, Mountjoy R, Quaye A. Quality Improvement project to evaluate current STOP-BANG Screening Tool Policies. Presented at Costas T. Lambrew Research Retreat, May 2, 2023

Quaye A, Robinson C, Hisey W, Mackenzie T, Butterly L. Propofol Based Sedation During Colonoscopy Associated with Increased Serrated Polyp Detection. A collaboration with Dartmouth Hitchcock Medical Center. Presented at AUA April 2023. Also presented at Costas T. Lambrew Research Retreat, May 2, 2023

Osuchukwu O. Institutional experience with unilateral Liposomal bupivacaine TAP block on pain score and opioid prescription at discharge following lap donor nephrectomy. APPM Conference 2023

Mountjoy R. It Started with a Text: How the COVID-19 Crisis Spurred a Successful Transition to Ambulatory Total Joint Arthroplasty. 2023 Maine Society of Anesthesiologists Annual Meeting.

Osuchukwu O. Perioperative management of chronic medications, laboratory values and EKG. Maine Society of PeriAnesthesia Nurses 2023 Spring Conference.

Quaye A. Postoperative Pain Severity and Opioid Consumption in Patients on Buprenorphine or Methadone for the Treatment of Opioid Use Disorder. Presented at ASA Annual Meeting 2022.

Quaye A. Current State of Perioperative Buprenorphine Management—A National Provider Survey. Presented at PGA 2022.

Quaye A; Osuchukwu O; Gagnon J; Nohr O. Liposomal bupivacaine compared to conventional bupivacaine in transversus abdominis plane blocks for elective lower abdominal surgery. Presented at the 2022 American Society of Regional Anesthesia and Pain Medicine annual meeting and to the 2022 International Anesthesia Research Society Annual Meeting.

Quaye A. Optimizing Perioperative Buprenorphine Management in Patients with Opioid Use Disorder. Northern New England Center for Clinical and Translational Research Seminar Series. May 26, 2023

Jenson A, Jashinski J, Cloutier A, Eastman S, Pachas G, Evins E, Quaye A, Gilman J. Can Patients Taper Opioid Medication and Maintain Pain Control? A randomized trial of cannabis added to behavioral pain management among adults with chronic non-cancer pain. A collaboration with Massachusetts General Hospital. Presented at Costas T. Lambrew Research Retreat, May 2, 2023

McGrory B, Mountjoy R, Hubbs R, Rana A, Mackenzie J, Hersch M, Becker M, Colacchio N. The Use of the iPack Block with the Adductor Canal Block Decreases 48-hour Narcotic Usage and Postoperative Pain following Total Knee Arthroplasty. Presented at Costas T. Lambrew Research Retreat, May 2, 2023

Budi T, Richard J, Craig W, Mountjoy R, Quaye A. Quality Improvement project to evaluate current STOP-BANG Screening Tool Policies. Presented at Costas T. Lambrew Research Retreat, May 2, 202

Quaye A, Robinson C, Hisey W, Mackenzie T, Butterly L. Propofol Based Sedation During Colonoscopy Associated with Increased Serrated Polyp Detection. A collaboration with Dartmouth Hitchcock Medical Center. Presented at AUA April 2023. Also presented at Costas T. Lambrew Research Retreat, May 2, 2023

Quaye A. Perioperative Buprenorphine- Optimizing Management Strategies. Invited lecture at Beth Israel Deaconness.

Gagnon J. Kellegrew J. McAuley P- ASA Practice Guidelines for the Management of a Difficult Airway- 2022 Update-MeSA PBLD, Carrabassett Valley Maine, Feb 2023

Peck M. Maquoit G. Upper Extremity Nerve Block in a Pulmonary Cripple MeSA PBLD, Carrabassett Valley Maine, Feb 2023

Senior Grand Rounds - Talitha Budi, MD, Portland ME May 2023

Senior Grand Rounds - Travis Barker MD, Portland ME, June 2023

Senior Grand Rounds - Gui Holck MD, Portland ME June 2023

Cardiac Conference Presentation, Jay Kellegrew MD, Portland, ME March 2023

Cardiac Conference Presentation, Gasper Gasperlin DO, Portland, ME February 2023

Cardiac Conference Presentation, Meredith Peck DO, Portland, ME April 2023

Cardiac Conference Presentation, Christine Kerr DO, Portland, ME May 2023

Cardiac Conference Presentation, Danielle Kerr DO, Portland, ME June 2023

Leadership Positions

• Michael Henry, MD - Medical student clerkship director
• Jonathan Meserve, MD - Maine Medical Association Board of Directors, healthcare reform and bylaws subcommittee
• Maryn Kanter, MD - MHMMC board liaison
• Jessica Hathaway, MD - MHMMC Executive Committee
• Adam O’Brien, DO - Treasurer MeSA

Publications

Quaye A, Ibrahim Y, Silva K, Richard J, Craig W, Rosen C. A Prospective, Randomized Trial of the Effect of Buprenorphine Continuation versus Dose Reduction on Pain Control and Post-Operative Opioid Use: a protocol. Medicine. 2022. Dec 23;101 (51):e32309 PMID: 36595741

Cobb J, Craig W, Richard J, Snow E, Turcotte H, Warters R, Quaye A. A Retrospective Study of Acute Postoperative Pain After Cesarean Delivery in Patients With Opioid Use Disorder Treated With Opioid Agonist Pharmacotherapy. J Addict Med. 2022 Sep-Oct 01;16(5):549-556.

Holck G, Quaye AN. Alternating bilateral Horner's syndrome during continuous thoracic epidural analgesia. Anaesth Rep. 2022;10(1):e12147.

Quaye A, C.; Riker, R.; May, T.; Sauer, W.; Seder, D., Gagnon, D. Buprenorphine ordering patterns during and after critical illness. Anesth Analg. 2022;134(5S):740-742.

Florman J; Rughani A; Kizor R; Pardi G; England E; Brown E. Awake Craniotomy without Invasive Blood Pressure Monitoring. World Neurosurgery, 2022-12-01, Volume 168, Pages e350-e353

Levin B; et al. One-Year Survival for Adult Venoarterial Extracorporeal Membrane Oxygenation Patients Requiring Renal-Replacement Therapy. Journal of Cardiothoracic Vascular Anesthesia. 2022 Jul;36(7):1942-1948.

Chang M; Sakano T; Levin B; Convissar D; Bittner E. Reduced Effective Oxygen Delivery and Ventilation with a Surgical Facemask Placed under Compared to over an Oxygen Mask: A Comparative Study. Anesthesiology Research and Practice, 2022.

Poltak J; Connors C; et al. Pharmacokinetics of Cefazolin in Patients With Obesity Undergoing Surgery Requiring Cardiopulmonary Bypass. Journal of Cardiothoracic Vascular Anesthesia. 2022 Aug;36(8 Pt B):2942-2947.

Quaye A, Wampole C, Riker RR, Seder DB, Sauer WJ, Richard JM, et al. Buprenorphine Continuation During Critical Illness Associated With Decreased Inpatient Opioid Use in Individuals Maintained on Buprenorphine for Opioid Use Disorder in a Retrospective Study. J Clin Pharmacol. 2023. Epub 2023/05/19. doi: 10.1002/jcph.2286. PubMed PMID: 37204408.

Quaye A, Mardmomen N, Mogren G, Ibrahim Y, Richard J, Zhang Y. Current State of Perioperative Buprenorphine Management-A National Provider Survey. J Addict Med. 2023. Epub 2023/06/05. doi: 10.1097/adm.0000000000001191. PubMed PMID: 37276022.

Faculty & Resident: Conferences Attended 2022-2023

• American Academy of Pain Medicine (AAPM)
• American Society Regional Anesthesia & Pain Medicine (ASRA)
• ASA Legislative Meeting
• ASA Annual Meeting
• ABA Board Examiners (Lennon, Hathaway, Allyn)
• ACGME
• MITE Faculty Development Conference
• Maine Society of Anesthesiologists (MeSA)
• Society Pediatric Anesthesia
• Society for Neuroscience in Anesthesiology and Critical Care (SNACC)
• Society Cardiovascular Anesthesiologists (SCA)
• International Anesthesia Research Society (IARS)
• International Meeting on Simulation in Healthcare
• Society of Academic Anesthesiology Association (SAAA)
• Society for Education in Anesthesia (SEA)
• Principles of Medical Education, Maximizing Your Teaching Skills

Current Prospective Research/QI Projects

• A Prospective, Randomized Trial of the Effect of Buprenorphine Continuation on Pain Control and Post-Operative Opioid Use - PI-Aurora Quaye MD; Silva; Talitha Budi MD, Meredith Peck DO *actively recruiting
• A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Continuous Nerve Catheters on Pain Control and Post-Operative Opioid Use in Receiving Popliteal Nerve Blocks for Below the Knee Amputation -PI—Ryan Mountjoy, MD, Co-PI—Aurora Quaye, MD*recruiting
• Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients with Chronic Non-Cancer Pain—in collaboration with Massachusetts General Hospital, local PI-Aurora Quaye, MD, PI-Jodi Gilman *actively recruiting
• Quality Improvement Initiative to Improve the Detection and Treatment of Hyperglycemia in Diabetics and non-diabetics undergoing Neurosurgery, Vascular Surgery or ERAS protocols at Maine Medical Center PI- Rob Hubbs MD/Patrick Hackett MD

Current Retrospective Projects

• Investigating the use of sedation in colonoscopy to optimize colorectal cancer prevention—in collaboration with Dartmouth- Aurora Quaye, MD
• The implication of frailty for the surgical patient- Nicolais, Rob Hubbs MD, Aurora Quaye, MD
• Predicting Persistent Opioid Use After Total Joint Arthroplasty—in collaboration with OHDSI-Aurora Quaye, MD
• Buprenorphine Utilization and Outpatient Opioid Dispensing in Patients Requiring Critical Care- Aurora Quaye, MD
• Institutional Experience with Liposomal Versus Conventional Bupivacaine for Transversus Abdominis Plane Blocks in Abdominal Surgeries- Aurora Quaye, MD, Jim Gagnon MD, Obiyo Osuchukwu, MD
• Postoperative Pain Control in Patients on Buprenorphine, Methadone or Naltrexone Treatment for Opioid Use Disorder- Aurora Quaye, MD
• Post-Operative Pain Following Cesarean Section in Patients on Opioid Agonist Pharmacotherapy receiving postoperative ketamine infusions- Aurora Quaye, MD, Talitha Budi, MD
• Evaluation of Current STOP-BANG Screening Tool Policies—Talitha Budi MD
• True Learn Question Use and Resident Performance on In-Training Exam- James Flowerdew MD, Travis Barker MD

Projects in Development

• Prospective pilot trial investigating Exparel vs conventional bupivacaine for c-section patients –Galina Korsunsky MD, Ryan Mountjoy MD, Aurora Quaye MD

Invited Lectures

• Ryan Mountjoy MD, Invited Guest Speaker, August 2021, Department of Anesthesiology at Kaiser in San Francisco, The Case for Regional Anesthesia in the Era of Multimodal Analgesia: Is Liposomal Bupivacaine the Icing on the Cake or an Expensive Trojan Horse?
• Ryan Mountjoy MD, MHMMC Department of Surgery, Grand Rounds, 10/21/21, Opioid-Induced Hyperalgesia and the Case for Multimodal Analgesia in the Perioperative Setting
• Adam O’Brien DO, Intubation Clinic at UNE, 11/6/21 for UNE Anesthesia and Emergency Medicine Clubs
• Adam O’Brien DO, Ultrasound for Regional Blocks for nurses at Goodall Hospital, 9/2/21
• Isaac Chemmanam MD, Harvard Beth Israel Pain Fellowship Program, 10/14/21, A Career in Pain Medicine and Anesthesiology
• Isaac Chemmanam MD, American Society of Anesthesiology Annual Scientific Meeting, 10/11/21, Invited Lecture, Predictors of Chronic Post-Surgical Pain
• Patrick Hackett MD, Venlafaxine overdose, presented to MHMMC ECMO department Portland, ME 8/2021

Conference Presentations

• Aurora Quaye MD, Obi Osuchukwu MD, Jim Gagnon MD, and Orion Nohr MD Liposomal bupivacaine compared to conventional bupivacaine in transversus abdominis plane blocks for elective lower abdominal surgery, accepted to the American Society of Regional Anesthesia and Pain Medicine annual meeting, the American Society of Anesthesiologists Meeting and to the International Anesthesia Research Society Annual Meeting
• Aurora Quaye MD, Billy Sauer MD, Yussr Ibrahim MD, Buprenorphine Ordering Patterns During and After Critical Illness, accepted to International Anesthesia Research Society Annual Meeting.
• Gui Holck MD Anesthetic management of the pregnant patient with pulmonary hypertension Monthly Academic virtual meeting, Society of Anesthesia of the estate of Rio de Janeiro, Brasil, October 25, 2022
• Travis Barker, MD/Anne Hicks MD A Case of Mistaken Identity? Constrictive Pericarditis, Cardiac Tamponade, or Both? SCA-5/14/22 Palm Springs CA
• Travis Barker, MD, Analysis of Transfusion Practices in Coronary Artery Bypass Grafting at a Large Tertiary Care Center as it Relates to Preoperative Hemoglobin and Patient Outcomes, SCA 5/16/22 Palm Springs CA
• Paul Lennon, MD/David Hales MD, Echocardiographic Guided Removal of an Embolic Tricuspid Valve Vegetation SCA-5/14/22 Palm Springs CA
• Paul Lennon, MD Another Option for Treating a Patient with Decompensated Aortic Valve Stenosis and Cardiogenic Shock SCA, 5/17/22 SCA Palm Springs CA
• Meredith Peck, DO Treatment of Chronic Shoulder Pain Using the Facial Distortion ModelMaine Osteopathic Association, 6/10/22, Rockport ME
• Rob Hubbs MD, Pat Hackett MD, and Aurora Quaye MD, Improving Perioperative Hyperglycemic Control accepted for the ASA meeting in October!
• Meredith T Peck, D.O., Ruslan Abdukalikov, D.O., Obiyo Osuchukwu, MD Trigger point injection of local anesthetic agents in the treatment of myofascial pain syndrome, ASRA Fall 2021, Orlando, FL
• Isaac Chemmanam MD, Identifying people at risk for chronic pain ASA meeting San Diego, CA October 11, 2021
• Galina Korsunsky MD Ambulatory Arthroplasties ASA meeting San Diego, CA October 11, 2021
• Jim Pisini DO, Derek Bunch DO, Meredith Peck DO, Anesthesia for Hip Fractures, PBLD presentation MeSA meeting, February 2022
• Jim Gagnon MD, Obi Osuchukwu MD, General Anesthesia in Covid-19 Lung, PBLD presentation MeSA meeting, February 2022
• Chris Abruzzese DO, Talitha Budi MD, Gasper Gasperlin DO, Perioperative Anaphylaxis in Children, PBLD presentation MeSA meeting, February 2022
• Adam O’Brien DO, Travis Barker MD, Jay Kellegrew MD, Perioperative Management of Cardiac Implantable Electronic Devices, PBLD presentation MeSA meeting, February 2022
• Senior Grand Rounds- Fascial Plane Blocks, Derek Bunch DO, Portland ME, May 2022
• Senior Grand Rounds- Updates on Management of Cancer Pain, Yussr Ibrahim MD, Portland ME May 2022
• Senior Grand Rounds- Global Health – Pitfalls & Ethical Considerations, Maryn Kanter MD, Portland ME June 2022
• Senior Grand Rounds- Distraction in the Operating Room, Heather Turcotte, DO, Portland ME May 2022
• Cardiac Conference Presentation, Gui Holck MD, Portland, ME February 2022
• Cardiac Conference Presentation, Travis Barker MD, Portland, ME March 2022
• Cardiac Conference Presentation, Talitha Budi MD, Portland, ME April 2022

Challenging Case Conferences

• Challenging Case Conference- Epidural Hematomas- Eric Brown MD- July 1, 2021
• Challenging Case Conference- Bob Ascanio, MD- November 11, 2021

Leadership Positions

• Chris Beeler, MD - Medical student clerkship director, Member, EVAC committee
• Jonathan Meserve MD -Maine Medical Association Board of Directors, healthcare reform and bylaws subcommittee
• Maryn Kanter MD - MHMMC board liaison
• Jessica Hathaway MD - MHMMC Executive Committee
• Adam O’Brien DO - Treasurer MeSA

Publications

• Ryan Mountjoy MD, Anesthesiology News, part of an ongoing case series, “From the Bench to the Bedside", "Nonopioid Strategies for Postsurgical Pain Management, Outpatient Shoulder Surgery"
• Cobb J, Craig W, Richard J, Snow E, Turcotte H, Warters R, Quaye A. Low-dose ketamine infusion for post-cesarean delivery analgesia in patients with opioid use disorder. Int J Obstet Anesth. 2021 Aug;47:103170. doi: 10.1016/j.ijoa.2021.103170. Epub 2021 May 2. PubMed PMID: 34090769.
• Smith K, Wang M, Abdukalikov R, McAullife A, Whitesell D, Richard J, Sauer W, Quaye A. Pain Management Considerations in Patients With Opioid Use Disorder Requiring Critical Care. J Clin Pharmacol. 2022 Apr;62(4):449-462. doi: 10.1002/jcph.1999. Epub 2022 Jan 5. Review. PubMed PMID: 34775634.
• Holck G, Quaye AN. Alternating bilateral Horner's syndrome during continuous thoracic epidural analgesia. Anaesth Rep. 2022 Jan-Jun;10(1):e12147. doi: 10.1002/anr3.12147. eCollection 2022
• Douin DJ, Krause M, Williams C, Tanabe K, Fernandez-Bustamante A, Quaye AN, Ginde AA, Bartels K. Corticosteroid Administration and Impaired Glycemic Control in Mechanically Ventilated COVID-19 Patients. Semin Cardiothorac Vasc Anesth. 2022 Mar;26(1):32-40. doi: 10.1177/10892532211043313. Epub 2021 Sep 2.
• Jashinski J, Grossman E, Quaye A, et al. Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol. BMJ Open. 2022;12(6):e064457.
• Cobb J, Craig W, Richard J, Snow E, Turcotte H, Warters R, Quaye A, A Retrospective Study of Acute Postoperative Pain After Cesarean Delivery in Patients With Opioid Use Disorder Treated With Opioid Agonist Pharmacotherapy. J Addict Med. 2022.
• Levin B, Ortoleva J, Tagliavia A, et al. One-Year Survival for Adult Venoarterial Extracorporeal Membrane Oxygenation Patients Requiring Renal-Replacement Therapy. J Cardiothorac Vasc Anesth. 2021.
• Chang MG, Sakano T, Levin BS, Convissar D, Bittner EA. Reduced Effective Oxygen Delivery and Ventilation with a Surgical Facemask Placed under Compared to over an Oxygen Mask: A Comparative Study. Anesthesiol Res Pract. 2022;2022:4798993.
• Levin BS, Chang MG, Bittner EA Teleguidance Technology for Endotracheal Intubation: A Scoping Review. Crit Care Explor. 2021 Dec 9;3(12):e0582. doi: 10.1097/CCE.0000000000000582. eCollection 2021 Dec.
• Poltak J, Connors C, Wungwattana M, Nicolau D, Mercuro NJ, Liu J. Pharmacokinetics of Cefazolin in Patients With Obesity Undergoing Surgery Requiring Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2022;36(8 Pt B):2942-2947.
• Nwanna-Nzewunwa OC, Lennon P, Gebhardt BR, Couper G, Robich MP. Facial Plethora and Markedly Elevated Central Venous Pressure After Mitral Valve Repair, Maze, and Left Atrial Appendage Occlusion Procedures. J Cardiothorac Vasc Anesth. 2022;36(6):1804-1806.
• Lennon P. Typical Dose of Intravenous Norepinephrine Administered Peripherally. Anesth Analg. 2022;134(1):e5.
• Hackett P. Rescue venoarterial extracorporeal membrane oxygenation in venlafaxine overdose: a case report. Journal of Emergency and Critical Care Medicine. (In Press) https://jeccm.amegroups.com/article/view/7417/html
• Kwock J, Patient Transport in the Time of COVID-19: Using Health Care Failure Mode and Effect Analysis with Simulation to Test and Modify a Protocol JMMC > Vol. 3 (2021) > Iss. 2
• Allyn, John W. MDa,b,; Curry, Craig S. MDa,b; Hubbs, P. Robert MDa,b; Hicks, Anne MDa,b; Craig, Wendy PhDc; Muns, Emily MDd; Susser, Philip BSe; Richard, Janelle M. BA, CCRPa; Atkins, Joshua H. MD, PhD, Variability in the criteria for a difficult intubation alert in the age of videolaryngoscopy: a scenario-based, multidisciplinary, multi-institutional provider survey. Journal of Head & Neck Anesthesia: December 2021 - Volume 5 - Issue 2 - p e37
• ED 90 of Intrathecal Chloroprocaine With Fentanyl for Prophylactic Cervical Cerclage: A Sequential Allocation Biased-Coin Design. Sharawi N, Tan HS, Taylor C, Fuller ME, Landreth RA, Diomede OI, Williams M, Martinello C, Mhyre JM, Habib AS.Anesth Analg. 2022 Apr 1;134(4):834-842.
• Quality of Labor Analgesia with Dural Puncture Epidural versus Standard Epidural Technique in Obese Parturients: A Double-blind Randomized Controlled Study. Tan HS, Reed SE, Mehdiratta JE, Diomede OI, Landreth R, Gatta LA, Weikel D, Habib AS.Anesthesiology. 2022 May 1;136(5):678-687.

Submitted for Publication

• Osuchukwu O, Gagnon J, Richard J, Craig W, Quaye A. Liposomal bupivacaine in transversus abdominis plane blocks for lower abdominal surgery. Pain Practice
• Quaye A, Mardmomen N, Mogren G, Ibrahim Y, Richard J, Zhang Y. Current State of Perioperative Buprenorphine Management—A National Provider Survey. Journal of Addiction Medicine
• Peck, M, co-author "LGBQ+ Health" to be published in The International Encyclopedia for Health Communication

Faculty & Resident: Conferences Attended 2021-2022

American Academy of Pain Medicine (AAPM)
American Society Regional Anesthesia & Pain Medicine (ASRA) 
ASA Legislative Meeting 
ASA Annual Meeting
ABA Board Examiners (Lennon, Hathaway, Allyn)
ACGME
MITE Faculty Development Conference
Maine Society of Anesthesiologists (MeSA)
Society Pediatric Anesthesia
Society for Neuroscience in Anesthesiology and Critical Care (SNACC) 
Society Cardiovascular Anesthesiologists (SCA)
International Anesthesia Research Society (IARS) 
International Meeting on Simulation in Healthcare 
Society of Academic Anesthesiology Association (SAAA)
Society for Education in Anesthesia (SEA)
Principles of Medical Education, Maximizing Your Teaching Skills